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Histamine Intolerance

Histamine is a naturally occurring organic nitrogenous chemical found across a variety of both plants and animals. So far, the compound has been found to play a role in over 23 different processes in the body. Histamine conducts a critical role in the body's immune system towards pathogens by causing an inflammatory response, causing the capillaries in the affected region to enlarge, enabling the white blood cells to flow freely and deal with the pathogens.

Histamine additionally plays a role in the physiological functioning of the gastrointestinal (GI) tract and is also involved with the nervous system as a neurotransmitter. The chemical regulates the state of alertness in the body. Consequently, a lack of the compound may result in a state of drowsiness and lowered or impaired mobility and slower reactions. But, at the other end, an imbalance caused by an excess can cause a prolonged state of alertness which could be equally harmful in the long run. Histamine is also used by the body in gastric acid release where it plays the role

of stimulating the parietal cells in the stomach and causes them to start the process of realising gastric acid. As pH levels drop, production of the chemical is stopped as well. An excess of the compound can cause acidity and associated problems as a consequence. Furthermore, it has also been linked with many other functions and body mechanisms including schizophrenia, sexual functions including erection and maintaining libido, multiple sclerosis (use of histamine for its treatment is being widely researched), etc.

Despite being an essential part of numerous bodily functions, an excess of histamine can nevertheless cause severe responses, including allergic reactions to occur. The body normally deals with such an excess on its own, with the release of antihistamines and related chemicals, but sometimes, if a large amount of the chemical is ingested through particular foods, or in the case of extremely rare disorders like mastocystosis (causes an excess of the compound from overproduction of mast cells), the body cannot neutralise the excess store fast enough.

The threshold for excess histamine varies from individual to individual, and when this threshold is crossed for the first time, the body may produce antibodies to fight the chemical which it perceives as an allergen (an agent that causes allergy). Exposure to excess histamine in such individuals later on brings on an allergic reaction that can have adverse effects. Common symptoms of histamine intolerance include difficulty in breathing (asthma), bloating and cramping in the stomach, headaches, arrhythmia (irregular heart beat), tachycardia (elevated heart beat rate), sudden outburst of acne, or skin rashes and eczema, low blood pressure, menstrual pain and cramps, etc.

If have experienced any of these symptoms, it is advisable to seek medical counselling immediately. Reduction of histamine releasing foods is also recommended – alcohol, bananas, chocolate, cocoa, citrus fruits, eggs, tea, pineapples, papayas, pulses, tomatoes, wheat germ, etc. Consultation with a medical professional is essential for creating an appropriate diet. Our ImuPro series of tests are ideal to determine your body's reactions to various food items in your regular or non-regular diet. We recommend our users to go for the comprehensive ImuPro300 that checks for 270 food items and helps ensure they don't eat anything that causes problems. Individuals can also opt for a step-wise plan that checks for 90 items first, then another 90 (total 180) and finally another 90 (total 270).

Contact Information

  • +91 8800929600
  • +91 011-42381323
  • neeraj.arora@cmdsingapore.com

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